国立感染症研究所

Jpn. J. Infect. Dis., 65 (1), 33-36, 2012

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Koichi Izumikawa1, Yoshihiro Yamamoto1*, Katsunori Yanagihara2, Takayoshi Kiya2, Junichi Matsuda2, Yoshitomo Morinaga2, Shintaro Kurihara3, Shigeki Nakamura1, Yoshifumi Imamura1, Taiga Miyazaki1, Tomoya Nishino1, Misuzu Tsukamoto1, Hiroshi Kakeya1, Akira Yasuoka3, Takayoshi Tashiro3, Shimeru Kamihira2, and Shigeru Kohno1

1Department of Molecular Microbiology and Immunology, 4Division of Scientific Data Registry, Atomic Bomb Disease Institute, and 5Department of Health Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501; and 2Department of Laboratory Medicine and 3Nagasaki University Infection Control and Education Center, Nagasaki University Hospital, Nagasaki 852-8501, Japan

(Received August 4, 2011. Accepted October 31, 2011)


*Corresponding author: Mailing address: Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan. Tel: +81-95-819-7273, Fax: +81-95-849-7285, E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.


SUMMARY: The utility of active surveillance cultures (ASCs) in respiratory wards, that do not have an associated intensive care unit (ICU), and the usefulness of the BD GeneOhm MRSATM system for rapid detection of methicillin-resistant Staphylococcus aureus (MRSA) have not been previously evaluated in Japan. ASCs using conventional culture methods and the BD GeneOhm MRSATM assay were conducted in adult inpatients between May 11, 2009 and November 10, 2009 in a respiratory ward, without an associated ICU, in Nagasaki University Hospital. The infection and colonization rates of MRSA acquired in this respiratory ward were both investigated. A total of 159 patients were investigated. Of these, 12 (7.5%) were found positive for MRSA by the BD GeneOhm MRSATM assay and 9 (5.7%) were found positive by a conventional culture test upon admission. All cases were MRSA-colonized cases and cross-transmission was not found to occur during hospitalization. The BD GeneOhm MRSATM assay had a sensitivity of 100% and a specificity of 98%. ASCs in our respiratory ward revealed that MRSA was brought in from other sites in some cases, and that current infection control measures in Nagasaki University Hospital are effective. The BD GeneOhm MRSATM assay was proven to be a useful and rapid detection tool for MRSA.

Copyright 1998 National Institute of Infectious Diseases, Japan

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