Jpn. J. Infect. Dis., 58 (6), 366-368, 2005

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Short Communication

Pyogenic Liver Abscess: A Retrospective Analysis of 107 Patients during a 3-Year Period

Khee-Siang Chan, Chin-Ming Chen, Kuo-Chen Cheng, Ching-Cheng Hou, Hung-Jung Lin1 and Wen-Liang Yu*

Department of Intensive Care Medicine and 1Department of Emergency Medicine, Chi Mei Medical Center, Tainan, Taiwan

(Received June 10, 2005. Accepted September 6, 2005)


*Corresponding author: Mailing address: Department of Intensive Care Medicine, Chi-Mei Medical Center, No. 901 Chung-Hwa Road, Yung-Kang City, Tainan, Taiwan 710, ROC. Tel: +886-6-281-2811 ext. 57351, Fax: +886-6-282-8928, E-mail: yuleon_md@yahoo.com.tw


SUMMARY: Pyogenic liver abscess (PLA) is a potentially life-threatening disease, and early diagnosis may be difficult. In order to provide diagnostic clues and to enhance the prompt management of such cases, we retrospectively investigated the clinical characteristics of PLA during a 3-year period in a tertiary-care hospital. The crude incidence rate of PLA in our study was 446.1 per 100,000 hospital admissions. Male predominance and a mean age of 57.6 +/- 14.4 years were observed. Diabetes mellitus was the most common concomitant disease, and biliary pathologies were the most common predisposing cause of this type of abscess. The most common clinical features were fever, chills, and abdominal pain. Leukocytosis was found in 67.3% of the patients, and the observed C-reactive protein (CRP) values were high. The most common pathogen was Klebsiella pneumoniae. The mortality rate was 6.5%. A complete history, physical examination, evaluation of the white blood cell count and CRP, and the prompt arrangement of imaging studies may lead to an earlier diagnosis. The aggressive performance of image-guided catheter drainage and the appropriate administration of antibiotics may reduce the mortality rate of PLA.


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