The research activities in this department are as follows; classification, identification, serotyping and molecular typing of pathogenic bacteria described below for the diagnosis and investigation of community- and hospital- acquired bacterial infections. Molecular analysis of virulence of such bacteria has been intensively made, which outcomes are applied to the development of new methods for early diagnosis, and effective treatment and prevention.

LABORATORY OF ENTERIC INFECTION I

Research on molecular genetics of enteric pathogenic bacteria such as enterohemorrhagic Escherichia coli and Campylobacter spp.
Development of molecular epidemiological methods for outbreak investigations of enteric pathogenic bacteria.
Research on molecular interaction of enteric pathogenic bacteria with host cells.

LABORATORY OF ENTERIC INFECTION II

Classification, identification, serotyping and etiology of family of Vibrionaceae and Shigella.
Phage typing and etiology of Salmonella enterica serovar Typhi and Paratyphi A.
Molecular analysis of Shigella, Salmonella enterica serovar Typhi and Vibrio infections.

LABORATORY OF EMERGING INFECTION

Molecular Epidemiology and Pathogenicity of Legionella.
Epidemiology and Antimicrobial Resistance in Invasive Pneumococcal Disease.
Molecular Analysis of Pneumococcal Virulence Factor Functions and Bacteria-Host Interactions.
Molecular Analysis and Surveillance of Invasive Streptococcal Infection.

LABORATORY OF SYSTEMIC INFECTION

Development of diagnostic materials for Lyme disease, leptospirosis and plague.
Molecular analysis of virulence of Borrelia and Leptospira.

LABORATORY OF UROGENITAL INFECTION

Development of evaluation of diagnostic materials for syphilis.
Molecular analysis of virulence and diagnosis of drug resistance in urogenital infectious bacteria.
Molecular analysis and surveillance of Neisseria meningitidis.

LABORATORY OF ORAL BACTERIAL INFECTION

Development of diagnostic and preventive measures against oral bacterial infectious diseases.
Molecular analysis of pathogenesis of pathogenic oral bacteria.
Biology and medical applications of bacterial membrane vesicles.