1. Tóth EA, Oszvald Á, Péter M, Balogh G, Osteikoetxea-Molnár A, Bozó T, Szabó-Meleg E, Nyitrai M, Derényi I, Yamaji T, Hanada K, Vígh L, and *Matkó J (2017) Nanotubes connecting B lymphocytes: High impact of differentiation-dependent lipid composition on their growth and mechanics, Biochim Biophys Acta, 1862, 991-1000. doi: 10.1016/j.bbalip.2017.06.011.
  2. *Hanada K (2017) Ceramide transport from the endoplasmic reticulum to the trans Golgi region at organelle membrane contact sites, in "Organelle Contact Sites: From Molecular Mechanism to Diseases" (Eds., Mitsuo Tagaya & Thomas Simmen), Series: Advances in Experimental Medicine and Biology, Vol.997, pp69-81, Springer. DOI: 10.1007/978-981-10-4567-7 (査読無し)
  3. *Hanada K, and Sugiki T (2017) In vitro assay to extract specific lipid types from phospholipid membranes using lipid-transfer proteins: a lesson from the ceramide transport protein CERT, in “Lipidomics” (Ed., Paul Wood), Series: Neuromethods, Vol.125, pp81-98, Springer. Doi: 10.1007/978-1-4939-6946-3_6.
  4. *Oh H, Shin J, Ato M, Ma X, Williams D, Han K, Kim YJ, Kang HG, Jung K, Hanada K, Ochiai M, Hug PV, Park S, and Ahn C (2017) Meeting report: The first meeting of the national control laboratories for vaccines and biologicals in the Western pacific in 2016, Osong Public Health Res Perspect, 8, 91-103. Doi: org/10.24171/j.phrp.2017.8.1.13


  1.  *Yamaji T, Horie A, Tachida Y, Sakuma C, Suzuki Y, Kushi Y, and Hanada K (2016) Role of intracellular lipid logistics in the preferential usage of very long chain-ceramides in glucosylceramide, Int J Mol Sci,17, 1761. doi: 10.3390/ijms17101761 
  2. Hernández-Tiedra S, Fabrias G, Salanueva IJ, Casas J, Dávila D, Montes RL, Antón Z, García-Taboada E, Salazar M, Lorente M, Nylandsted J, Armstrong J, López-Valero I, McKee CS, García-López R, Serrano A, Abad JL, Hanada K, Goñi FM, Guzmán M, Lovat P, Jäättelä M, Alonso A, and *Velasco G (2016) Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization, Autophagy,12, 2213-2229. doi: 10.1080/15548627.2016.1213927
  3. Shirasago Y, Shimizu Y, Tanida I, Suzuki T, Suzuki R, Sugiyama K, Wakita T, Hanada K, Yagi K, Kondoh M, and *Fukasawa M (2016) Occludin-knockout human hepatic Huh7.5.1-8-derived cells are completely resistant to hepatitis C virus infection, Biol Pharm Bull, 39, 839–848. doi: 10.1248/bpb.b15-01023


  1. Sawada K, Sato T, Hamajima H, Jayakody NL, Hirata M, Yamashiro M, Tajima M, Mitsutake S, Nagao K, Tsuge K, Abe F, Hanada K, and *Kitagaki H (2015) Glucosylceramide contained in mold-cultured cereal confers membrane and flavor modification and stress tolerance to yeast during co-culture fermentation, Appl Environ Microbiol, 81, 3688-3698. doi:10.1128/AEM.00454-15
  2. *Fukasawa M, Nagase S, Shirasago Y, Iida M, Yamashita M, Endo K, Yagi K, Suzuki T, Wakita T, Hanada K, Kuniyasu H, and Kondoh M (2015) Monoclonal antibodies against extracellular domains of claudin-1 block hepatitis C virus infection in a mouse model, J Virol, 89, 4866-4879. doi: 10.1128/JVI.03676-14
  3. *Kang H, Xu M, Rodríguez VP, Mefed K, Hanada K, Ahn K, Gangakhedkar SJ, Pakzad SR, Prawahju EI, Lee N, Phumiamorn S, Nemec M, Meng S, Knezevic I (2015) Review of the current use and evaluation of cell substrates for producing biologicals in selected countries, Biologicals, 43, 153-157. doi: 10.1016/j.biologicals.2015.01.004
  4. Zhao Y, Ishigami M, Nagao K, Hanada K, Kono N, Arai H, Matsuo M, Kioka N, *Ueda K (2015) ABCB4 exports phosphatidylcholine in a sphingomyelin-dependent manner, J Lipid Res, 56, 644-652. doi: 10.1194/jlr.M056622
  5. Saito K, Suzuki T, Aizaki H, Hanada K, Wakita T, Nishijima M, *Fukasawa M (2015) Targeting cellular squalene synthase, an enzyme essential for cholesterol biosynthesis, is a potential antiviral strategy against hepatitis C virus. J Virol, 89, 2220-2232. doi:10.1128/JVI.03385-14
  6. *Yamaji T, and Hanada, K (2015) Sphingolipid metabolism and interorganellar transport: localization of sphingolipid enzymes and lipid transfer proteins, Traffic, 16, 101-122. doi: 10.1111/tra.12239
  7. Shirasago Y, Sekizuka T, Saito K, Suzuki T, Wakita W, Hanada K, Kuroda M, Abe R, *Fukasawa M (2015) Isolation and characterization of a Huh.7.5.1-derived cell clone highly permissive to hepatitis C virus. Jpn J Infect Dis, 68, 81-88. doi: 10.7883/yoken.JJID.2014.231
  8. Tanida I, Shirasago Y, Suzuki R, Abe R, Wakita T, Hanada K, and *Fukasawa M (2015) Inhibitory effects of caffeic acid, a coffee-related organic acid, on the propagation of hepatitis C virus, Jpn J Infect Dis, 68, 268-275. doi: 10.7883/yoken.JJID.2014.309


  1. Osada N, Kohara A, Yamaji T, Hirayama N, Kasai F, Sekizuka T, Kuroda M, *Hanada K (2014) The genome landscape of the African green monkey kidney-derived Vero cell line, DNA Res, 21, 673-683. doi: 10.1093/dnares/dsu029 (N.O. and A.K. equally contributed to this paper, and thus are co-first authors) (Open access: http://dnaresearch.oxfordjournals.org/content/21/6/673)
  2. Khan I, Katikaneni DS, Han Q, Sanchez-Felipe L, Hanada K, Ambrose RL, Mackenzie JM, and *Konan KV (2014) Modulation of hepatitis C virus genome replication by glycosphingolipids and four-phosphate adaptor protein 2, J Virol, 88, 12276-12295. doi:10.1128/JVI.00970-14
  3. *Hanada K, Voelker D (co-guest editors) (2014) Interorganelle trafficking of lipids: preface for the thematic review series, Traffic, 15, 889-894. doi:10.1111_tra.12193 (Open access:: http://onlinelibrary.wiley.com/doi/10.1111/tra.12193/epdf)(本論文が掲載された号の表紙に花田の作成した図が採用された)
  4. *Ogawa M, *Fukasawa M, Satoh M, Hanada K, Saijo M, Uchiyama T, and Ando S (2014) The intracellular pathogen Orientia tsutsugamushi responsible for scrub typhus induces lipid droplet formation in mouse fibroblasts, Microbe Infect., 16, 962-966. doi: 10.1016/j.micinf.2014.09.004
  5. Sano O, Ito S, Kato R, Shimizu Y, Kobayashi A, Kimura Y, Kioka N, Hanada K, Ueda K, and *Matsuo M: ABCA1, ABCG1, and ABCG4 are distributed to distinct membrane meso-domains and disturb detergent-resistant domains on the plasma membrane, PLoS One, 9, e109886. doi: 10.1371/journal.pone.0109886
  6. Hasegawa Y, *Hayashi H, Naoi S, *Kondou H, Bessho K, Igarashi K, Hanada K, Nakao K, Kimura T, Konishi A, Nagasaka H, Miyoshi Y, Ozono K, Kusuhara H (2014) Intractable itch relieved by 4-phenylbutyrate therapy in patients with progressive familial intrahepatic cholestasis type 1, Orphanet J Rare Dis, 9, 89. doi:10.1186/1750-1172-9-89
  7. *Maehama T, Kawahara K, Nishio M, Suzuki A, Hanada K (2014) Nucleolar stress induces ubiquitination-independent proteasomal degradation of PICT1, J Biol Chem, 289, 20802-20812. doi: 10.1074/jbc.M114.571893
  8. Kumagai K, Kawano-Kawada M, *Hanada K (2014) Phosphoregulation of the ceramide transport protein CERT at serine 315 in the interaction with VAMP-associated protein (VAP) for inter-organelle trafficking of ceramide in mammalian cells, J Biol Chem, 289, 10748-10760. Open access:https://doi.org/10748-10760. 10.1074/jbc.M113.528380
  9. *Yamaji T, *Hanada K (2014) Establishment of HeLa cell mutants deficient in sphingolipid-related genes by using TALENs, PLoS ONE, 9, e88124. 10.1371/journal.pone.0088124. (Open access: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0088124)
  10. Kajiwara K, Ikeda A, Aguilera-Romero A, Castillon GA, Kagiwada S, Hanada K, Riezman H, Muniz M, *Funato K (2014) Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast, J Cell Sci, 127, 376-387. 10.1242/jcs.132001.
  11. *Hanada K (2014) Co-evolution of sphingomyelin and the ceramide transport protein CERT, Biochim Biophys Acta, 1841, 704-719. doi: 10.1016/j.bbalip.2013.06.006 [Corrigendum (2014) 1841, 1561-1562; doi: 10.1016/j.bbalip.2014.08.002].

Copyright 1998 National Institute of Infectious Diseases, Japan

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