国立感染症研究所

花田研究業績（2022-） - 2009-2013

詳細

記事インデックス

4 / 7 ページ

2013年

  1. *Maehama T, Fukasawa M, Date T, Wakita T, Hanada K (2013) A class II phosphoinositide 3-kinase plays an indispensable role in hepatitis C virus replication, Biochem Biophys Res Commun, 440, 150-156. doi: 10.1016/j.bbrc.2013.09.048.
  2. *Kukimoto I, Maehama T, Sekizuka T, Ogasawara Y, Kondo K, Kusumoto-Matsuo R, Mori S, Ishii Y, Takeuchi T, Yamaji T, Takeuchi F, Hanada K, Kuroda M (2013) Genetic variation of human papillomavirus type 16 in individual clinical specimens revealed by deep sequencing, PLoS One, 8, e80583. doi: 10.1371/journal.pone.0080583.
  3. *Hagiwara K, Hara H, Hanada K (2013) Species-barrier phenomenon in prion transmissibility from a viewpoint of protein science, J Biochem, 153, 139-145. doi: 10.1093/jb/mvs148.
  4. Pratt S, Wansadhipathi-Kannangara NK, Bruce CR, Mina JG, Shams-Eldin H, Casas J, Hanada K, Schwarz RT, Sonda S, *Denny PW, Sphingolipid synthesis and scavenging in the intracellular apicomplexan parasite, Toxoplasma gondii, Mol Biochem Parasitol, 187, 43-51. doi: 10.1016/j.molbiopara.2012.11.007.

2012年

  1. Abe M, Makino A, Hullin-Matsuda F, Kamijo K, Ohno-Iwashita Y, Hanada K, Mizuno H, Miyawaki A, *Kobayashi T (2012) A role for sphingomyelin-rich lipid domains in the accumulation of phosphatidylinositol-4,5-bisphosphate to the cleavage furrow during cytokinesis, Mol Cell Biol, 32, 1396-1407. doi: 10.1128/MCB.06113-11.
  2. Sugiki T, Takeuchi K, Yamaji T, Takano T, Tokunaga Y, Kumagai K, Hanada K, *Takahashi H, *Shimada I (2012) Structural basis for the Golgi association by the pleckstrin homology domain of the ceramide trafficking protein (CERT), J Biol Chem, 287, 33706-33718. doi: 10.1074/jbc.M112.367730.
  3. Kumagai K, Nishijima M, *Hanada K (2012) Reconstitution assay system for ceramide transport with semi-intact cells, Methods Cell Biol, 108, 117-129. doi: 10.1016/B978-0-12-386487-1.00006-7.
  4. Hullin-Matsuda F, Tomishige N, Sakai S, Ishitsuka R, Ishii K, Makino A, Greimel P, Abe M, Laviad EL, Lagarde M, Vidal H, Saito T, Osada H, Hanada K, Futerman AH, *Kobayashi T (2012) Limonoid compounds inhibit sphingomyelin biosynthesis by preventing CERT protein-dependent extraction of ceramides from the endoplasmic reticulum, J Biol Chem, 287, 24397-24411. doi: 10.1074/jbc.M112.356733.
  5. Hara H, Okemoto-Nakamura Y, Shinkai-Ouchi F, Hanada K, Yamakawa Y, *Hagiwara K (2012) Mouse prion protein (PrP) segment 100 to 104 regulates conversion of PrP(C) to PrP(Sc) in prion-infected neuroblastoma cells, J Virol, 86, 5626-5636. doi: 10.1128/jvi.06606-11.

2011年

  1. Tuuf J, Kjellberg MA, Molotkovsky JG, Hanada K, *Mattjus P (2011) The intermembrane ceramide transport catalyzed by CERT is sensitive to the lipid environment, Biochim Biophys Acta, 1808, 229-235. doi: 10.1016/j.bbamem.2010.09.011.
  2. Elwell CA, Jiang S, Kim JH, Lee A, Wittmann T, Hanada K, Melancon P, *Engel JN (2011) Chlamydia trachomatis co-opts GBF1 and CERT to acquire host sphingomyelin for distinct roles during intracellular development, PLoS Pathog, 7, e1002198. doi: 10.1371/journal.ppat.1002198.

2010年

  1. *Yamaji T, Nishikawa K, Hanada K (2010) Transmembrane BAX inhibitor motif containing (TMBIM) family proteins perturbs a trans-Golgi network enzyme, Gb3 synthase, and reduces Gb3 biosynthesis, J Biol Chem, 285, 35505-35518. doi: 10.1074/jbc.M110.154229.
  2. Tanaka M, Hara H, Nishina H, Hanada K, Hagiwara K, *Maehama T (2010) An improved method for cell-to-cell transmission of infectious prion, Biochem Biophys Res Commun, 397, 505-508. doi: 10.1016/j.bbrc.2010.05.143.
  3. Sugiki T, Takahashi H, Nagasu M, Hanada K, *Shimada I (2010) Real-time assay method of lipid extraction activity, Anal Biochem, 399, 162-167. doi: 10.1016/j.ab.2009.12.031.
  4. Shinkai-Ouchi F, Yamakawa Y, Hara H, Tobiume M, Nishijima M, Hanada K, *Hagiwara K (2010) Identification and structural analysis of C-terminally truncated collapsin response mediator protein-2 in a murine model of prion diseases, Proteome Sci, 8, 53. doi: 10.1186/1477-5956-8-53.
  5. *Separovic D, Kelekar A, Nayak AK, Tarca AL, Hanada K, Pierce JS, Bielawski J (2010) Increased ceramide accumulation correlates with downregulation of the autophagy protein ATG-7 in MCF-7 cells sensitized to photodamage, Arch Biochem Biophys, 494, 101-105. doi: 10.1016/j.abb.2009.11.023.
  6. Rivier AS, Castillon GA, Michon L, Fukasawa M, Romanova-Michaelides M, Jaensch N, Hanada K, *Watanabe R (2010) Exit of GPI-anchored proteins from the ER differs in yeast and mammalian cells, Traffic, 11, 1017-1033. doi: 10.1111/j.1600-0854.2010.01081.x.
  7. *Nakamura H, Wakita S, Suganami A, Tamura Y, Hanada K, Murayama T (2010) Modulation of the activity of cytosolic phospholipase A2alpha (cPLA2alpha) by cellular sphingolipids and inhibition of cPLA2alpha by sphingomyelin, J Lipid Res, 51, 720-728. doi: 10.1194/jlr.M002428.
  8. Kudo N, Kumagai K, Matsubara R, Kobayashi S, Hanada K, Wakatsuki S, *Kato R (2010) Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer, J Mol Biol, 396, 245-251. doi: 10.1016/j.jmb.2009.12.029.
  9. *Hanada K (2010) Intracellular trafficking of ceramide by ceramide transfer protein, Proc Jpn Acad Ser B Phys Biol Sci, 86, 426-437. doi: 10.2183/pjab.86.426. (Open access: https://www.jstage.jst.go.jp/article/pjab/86/4/86_4_426/_article)

2009年

  1. Tomishige N, Kumagai K, Kusuda J, Nishijima M, *Hanada K (2009) Casein kinase I{gamma}2 down-regulates trafficking of ceramide in the synthesis of sphingomyelin, Mol Biol Cell, 20, 348-357. doi: 10.1091/mbc.E08-07-0669. (Open access: http://www.molbiolcell.org/content/20/1/348.long)
  2. *Tanida I, Fukasawa M, Ueno T, Kominami E, Wakita T, Hanada K (2009) Knockdown of autophagy-related gene decreases the production of infectious hepatitis C virus particles, Autophagy, 5, 937-945.
  3. Nitahara-Kasahara Y, *Fukasawa M, Shinkai-Ouchi F, Sato S, Suzuki T, Murakami K, Wakita T, Hanada K, Miyamura T, Nishijima M (2009) Cellular vimentin content regulates the protein level of hepatitis C virus core protein and the hepatitis C virus production in cultured cells, Virology, 383, 319-327. doi: 10.1016/j.virol.2008.10.009.
  4. Momin AA, Park H, Allegood JC, Leipelt M, Kelly SL, *Merrill AH, Jr., Hanada K (2009) Characterization of mutant serine palmitoyltransferase 1 in LY-B cells, Lipids, 44, 725-732. doi: 10.1007/s11745-009-3316-4.
  5. *Hanada K, Kumagai K, Tomishige N, Yamaji T (2009) CERT-mediated trafficking of ceramide, Biochim Biophys Acta, 1791, 684-691. doi: 10.1016/j.bbalip.2009.01.006.（本論文が掲載された号の表紙に我々の研究結果が採用された）

Copyright 1998 National Institute of Infectious Diseases, Japan

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